Clot lysis induced by a monoclonal antibody against alpha 2-plasmin inhibitor
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منابع مشابه
Clot Lysis Induced by a Monoclonal Antibody Against a2-Plasmin Inhibitor
A monoclonal antibody (MoAb) to a -plasmin inhibitor designated JTPI-1 inhibited antiplasmin activity by interfering with formation of a2-plasmin inhibitor (a2-Pl)-plasmin complex. With this MoAb, we observed plasma clot lysis in vitro and evaluated the potential of JTPI-1 to serve as a new therapeutic agent for thrombolysis. After adding lThl labeled fibrinogen to plasma, clots were made by ad...
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An enzyme-linked immunosorbent assay (ELISA) has been developed for the quantification of alpha 1-antitrypsin-human leukocyte elastase (alpha 1AT-E) complexes. In the ELISA, the alpha 1AT-E complex is bound to a surface by rabbit antileukocyte elastase antibody, and the inhibitor-proteinase complex is quantified by a second antibody, rabbit anti-alpha 1-antitrypsin F(ab')2, labeled with alkalin...
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ژورنال
عنوان ژورنال: Blood
سال: 1989
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v74.8.2692.bloodjournal7482692